virus replication — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2283	Tripterifordin		HIV Protease
	Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.		HIV Protease
T38514	PMEDAP		Others , HIV Protease
	PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega...		Others , HIV Protease
T11669	IR415		HBV
	IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i...		HBV
T38237	2′-O-Methylcytidine		Nucleoside Antimetabolite/Analog , HCV Protease
	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G....		Nucleoside Antimetabolite/Analog , HCV Protease
T11539	HCV-IN-29		HCV Protease
	HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.		HCV Protease
T11541	HCV-IN-30		Others , HCV Protease
	HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).		Others , HCV Protease
T9212	IMB-301		Others , HIV Protease
	IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.		Others , HIV Protease
T8354	Triazavirin		Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
	Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T8371	ML188		Virus Protease , SARS-CoV
	ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.		Virus Protease , SARS-CoV
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease
	FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective ...
T7330	Nucleozin		Influenza Virus
	Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.		Influenza Virus
T14968	Cinanserin hydrochloride	SQ 10643	Influenza Virus , 5-HT Receptor
	Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus.		Influenza Virus , 5-HT Receptor
T9716	Ensitrelvir	S-217622	SARS-CoV
	Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM.		SARS-CoV
T14495	Baloxavir	Baloxavir acid,S-033447	Influenza Virus
	Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.		Influenza Virus
T0220	Foscarnet sodium	Phosphonoformate	Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
	Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.		Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
T9350	IMP-1088		Others , DNA/RNA Synthesis
	IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.		Others , DNA/RNA Synthesis
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T6439	Cetylpyridinium Chloride	Cetamium,Pristacin,Hexadecylpyridinium Chloride	Others , HBV , Antibacterial
	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.		Others , HBV , Antibacterial
T1623	Lopinavir	ABT-378	SARS-CoV , HIV Protease
	Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr...		SARS-CoV , HIV Protease